Next Vial review
The short answer: Next Vial's store prices compounded semaglutide at $199 a month and tirzepatide at $249, billed monthly with no membership, though another of its pages shows higher figures.
By LongevityGLP1 desk, Publisher
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Next Vial by the numbers
- From
- $199/mo · starting dose, month to month
- Prescribes
- Compounded semaglutide · Compounded tirzepatide
- Prescriber
- Online review or a video visit
- Pharmacy
- Named on its site
- States
- All 50 states
- Healthspan Score
- 67 out of 100
Our take on Next Vial
Next Vial sells compounded semaglutide and compounded tirzepatide from one product page with a plan picker. The month-to-month plan is $199 a month for semaglutide and $249 for tirzepatide, billed monthly, and there's no membership fee. The price includes ongoing provider care and an injection supply kit, and shipping is free on orders over a small minimum. You're billed when the medication ships, and Next Vial says it contacts you before each refill is charged, which makes it easier to stop in time.
Paying ahead brings the monthly rate down sharply. Next Vial sells 3-, 6- and 12-month plans for both drugs, and the 12-month plan works out to well under the month-to-month price per month. That's real money if you already know the medicine suits you, but you pay the plan total up front and all sales are final once medicine ships. Start month to month if this is your first GLP-1, and see the compounded semaglutide cost guide for how the monthly rate compares.
One thing to clear up before you order: Next Vial's own pages don't agree on price. Its separate weight-loss page shows higher 'starting at' figures for 4 weeks of medication, and a banner on the product page says plans run 'as low as' a figure above the semaglutide store price. The store's plan picker is where you buy, so treat its price as current, but confirm the amount on the checkout screen. The banner also promises one all-in price with personalized dosing; the page doesn't say outright that the price holds at every dose, so ask.
Next Vial names the people behind the care, which many sellers don't. Its FAQ says its provider network is MD Integrations, and that Manifest Pharmacy in Greer, South Carolina, fills prescriptions; its footer says compounded medicines are prepared under Section 503A. US board-certified physicians review your questionnaire, usually within about 24 hours, and some states require a video consultation or live chat. Its FAQ lists every state except Alaska, though its sign-up form includes Alaska.
Next Vial also sells NAD+, sermorelin, testosterone and other treatments. For weight loss, compare it on the compounded semaglutide lineup and the compounded tirzepatide lineup, and read whether compounded tirzepatide is safe before you choose a drug.
What Next Vial costs
| Product | Real monthly cost | |
|---|---|---|
| Compounded semaglutideInjection | $199/mo | $199/mo |
| Compounded tirzepatideInjection | $249/mo | $249/mo |
Prices are taken from Next Vial's own site and current as of this update. Real monthly cost folds in required fees and turns four-week billing into calendar months; that's our math.
Compounded semaglutide skips FDA approval: no one at the FDA judges whether it is safe, whether it works, or how well it was made before a pharmacy sends it out.
Want Next Vial's current price for your dose?
Your monthly price is the same through our link.
What signing up looks like
Pick a plan and start
Choose semaglutide or tirzepatide and a plan length on the product page, then start your online visit.
A physician reviews it
A US board-certified physician through MD Integrations reviews your questionnaire, usually within 24 hours. Some states need a video or chat.
Manifest Pharmacy fills it
Manifest Pharmacy in Greer, South Carolina, prepares the compounded medicine under Section 503A, Next Vial says.
Shipped, then refilled
Medicine ships with no signature needed and you're billed on shipment. Next Vial contacts you before each refill is charged.
Who prescribes, and the pharmacy
US-based, state-licensed doctors from MD Integrations, the provider network Next Vial names in its FAQ, review your intake and prescribe. Its FAQ names Manifest Pharmacy in Greer, South Carolina, as the pharmacy that may fill your prescription, and its footer says compounded medicines are prepared under Section 503A.
Where Next Vial does well
- Month-to-month plans for both GLP-1s with no membership fee, plus 3-, 6- and 12-month prepay options.
- Names its provider network, MD Integrations, and its pharmacy, Manifest Pharmacy in South Carolina.
- You're billed when medicine ships, and contacted before each refill is charged.
- Ongoing provider care and an injection supply kit are included in the plan price.
- Serves every state but Alaska per its FAQ, and says compounding follows Section 503A.
What to check first
- Its weight-loss page shows higher GLP-1 figures than the store. Confirm the amount on the checkout screen before paying.
- The lowest monthly rates need a 12-month prepay and sales are final once shipped. Start month to month first.
- It doesn't say whether the price holds at higher doses. Ask what you'll pay at the dose you expect to stay on.
- Medicine can't be returned once it ships. Cancel in your account before the refill notice if you want to stop.
- Its FAQ leaves out Alaska while its sign-up form includes it. Alaska residents should confirm before ordering.
It fits you if
You want a month-to-month compounded semaglutide or tirzepatide price with no membership, from a seller that names its pharmacy and provider network.
Look elsewhere if
You want one price stated the same way on every page, a stated same-price-at-every-dose policy, or refunds on medicine after it ships.
How Next Vial scored
on the compounded semaglutide lineup
67out of 100
- Price17 of 35
$199 a month at the starting dose, month to month, fees folded in. Full points at $90 or less, none at $300 or more.
- Care10 of 25
- Shown: Who prescribes
- Shown: A clinician reviews your intake
- Not shown: Labs and who pays
- Not shown: Follow-up schedule
- Not shown: Dose changes at no new fee
- Pharmacy25 of 25
- Shown: Pharmacy named
- Shown: Pharmacy state or type
- Shown: Brand or compounded is clear
- Shown: No "FDA-approved" claim for a compounded drug
- Clarity15 of 15
- Shown: Price before the intake questions
- Shown: Cancel and refund terms
- Shown: States served
Other lineups: Compounded tirzepatide 70
Also on these lineups: Semaglutide programs that also treat low testosterone: 10 of 36 · Tirzepatide programs that also treat low testosterone: 8 of 34 · Compounded tirzepatide under $250 a month: 22 of 36 · Compounded semaglutide under $200 a month: 25 of 41 · Compounded semaglutide programs in all 50 states: 16 of 38 · Compounded tirzepatide programs in all 50 states: 14 of 39
Three more providers to weigh
Brightmeds
From $140/mo
MEDVi
From $299/mo
CoreAge Rx
PartnerFrom $139/mo
Questions about Next Vial
- How much does Next Vial cost for GLP-1s?
- On the store's month-to-month plan, compounded semaglutide is $199 a month and compounded tirzepatide is $249, with no membership fee. 3-, 6- and 12-month plans lower the monthly rate but are paid up front. Its separate weight-loss page shows higher figures, so confirm at checkout.
- Which pharmacy does Next Vial use?
- Its FAQ names Manifest Pharmacy in Greer, South Carolina, and says compounded medicines are prepared under Section 503A.
- Can I cancel Next Vial?
- Yes. You can cancel or reorder in your account at any time, and Next Vial contacts you before each refill is billed. Medicine can't be returned once it ships.
- Which states does Next Vial serve?
- Its FAQ lists every state except Alaska, though its sign-up form includes Alaska. Confirm your state during the visit.
- Does Next Vial take insurance?
- No. Next Vial is self-pay, and its terms bar claims to Medicare or other payers.
Read next
Picked for the same drugs and questions as this page.
- ResearchWegovy side effects: what the label lists and how long they last
Every side effect on the current US label, with the placebo rate beside it, the timeline the trials describe, and the short list of symptoms that mean call today.
- Drug guideSemaglutide: how it works and the products that contain it
Semaglutide copies GLP-1, a hormone your gut releases after eating. It raises insulin only when blood sugar is high, lowers glucagon, slows stomach emptying and reduces appetite through the brain. That is why it lowers blood sugar and body weight. It is sold as Ozempic and Rybelsus for diabetes and as Wegovy for weight.
- Side by sideSemaglutide vs tirzepatide: what the head-to-head trials found
One drug acts on one gut-hormone receptor, the other on two. Here's what that difference did in the trials that tested them directly.
- ResearchMicrodosing GLP-1 drugs: the claims, the evidence and the risks
Low-dose GLP-1 programs are sold for longevity, wellness and maintenance. Here is what the labels, the trials and the first real-world data actually show.
Still weighing Next Vial?
Where this review comes from
- Next Vial GLP-1 medications product page
- Next Vial Weight-loss page
- Next Vial FAQ
- Next Vial returns and refund policy
Every fact here comes from Next Vial's own public pages. Partner fees aren't one of the four checks.