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LongevityGLP1

Defy Medical review

The short answer: Defy Medical prescribes semaglutide, tirzepatide and liraglutide after a long video consult, with no subscription. No medication price is published, so you learn the cost after labs and a visit.

By LongevityGLP1 desk, Publisher

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Defy Medical by the numbers

From
Ask for the ongoing total
Prescriber
Video visit with a clinician
Pharmacy
Not named on its site
States
49 states
Healthspan Score
25 out of 100
See plans on Defy Medical's site

Our take on Defy Medical

Defy Medical is a Tampa, Florida practice that has run hormone and weight care by telemedicine for more than a decade, led by medical director Dr. Justin Saya. Its GLP-1 menu is wider than most: semaglutide and tirzepatide as a once-weekly injection, an oral disintegrating tablet or liquid drops, plus daily liraglutide. Your provider picks the drug, the form and the starting dose with you. What the pages never say is whether the semaglutide or tirzepatide you'd receive is a brand-name product or a pharmacy-made version, so ask that first.

The money side works differently from a monthly GLP-1 plan. Defy says there are no subscriptions or contracts: you pay for each consult, lab order and medication order as you go, through its patient portal. That sounds flexible, and it is, but none of those prices are on the public pages. You see what the medication costs only after you have bought labs and booked a paid consult. If you want to compare monthly figures before you commit, programs on the GLP-1 pill lineup print theirs up front.

Care is built around testing. The weight-loss page recommends a full blood panel covering thyroid, metabolic, heart and kidney markers, cholesterol and hormones, to look for a cause behind stubborn weight. Lab orders stay valid for three months and can be renewed once at no charge. The first consult runs up to an hour, which is long for this category, and follow-ups are offered without a fixed schedule for weight care. Defy doesn't take insurance.

Read the refund rules before you book. The terms say all sales are final apart from account credits. A consult canceled less than 24 hours ahead, or missed, can be charged in full, and a visit isn't refunded because you weren't prescribed anything. Medication can't be returned once it leaves the pharmacy. Lab orders can be refunded within 90 days if no sample has been sent, and later turn into store credit minus a processing fee.

Two more things to know. The tirzepatide page says the drug is FDA approved for weight loss without telling you whether the product dispensed is the approved brand, and the tirzepatide guide explains why that difference matters. And the peptide page lists BPC-157, TB-500, epithalon, KPV and MOTS-c, which have no lawful compounding route, so leave them out of any plan. Defy serves every state except Mississippi.

What Defy Medical costs

A comparable ongoing monthly total is not established for Defy Medical. Confirm the treatment, supply period and all required fees before paying.

Other available treatments with a monthly total to confirm: Semaglutide (injection), Tirzepatide (injection), Liraglutide (injection), Semaglutide (dissolving tablet), Semaglutide (oral liquid), Tirzepatide (dissolving tablet), Tirzepatide (oral liquid).

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Your monthly price is the same through our link.

Check Defy Medical's plans

What signing up looks like

  1. Send your details

    Fill out the get-started form or take the quiz. A patient advocate contacts you about labs, records and next steps.

  2. Complete labs and a consult

    Buy the recommended blood panel, then meet a provider by telemedicine for up to an hour to set a plan.

  3. Order in the patient portal

    If you're prescribed a GLP-1, you order it in the portal. A pharmacy in Defy's network fills it; Defy doesn't ship drugs itself.

  4. Delivery and follow-up

    Medication ships to your door. You book follow-up visits as needed to adjust the plan, paying for each one.

Who prescribes, and the pharmacy

Defy's physicians and nurse practitioners, led by medical director Dr. Justin Saya, prescribe after a telemedicine consult. Defy says it works with an expansive network of pharmacies that follow USP and good manufacturing standards, but it doesn't name any of them or say whether they are 503A or 503B.

Where Defy Medical does well

  • Semaglutide and tirzepatide come as weekly shots, dissolving tablets or drops, so needle-shy patients have options.
  • The first telemedicine consult can run up to an hour, with a provider who reviews your full history.
  • No subscription or contract: you pay for each visit, lab order and medication order you choose.
  • A full blood panel looks for thyroid, metabolic and hormone causes before a weight plan is set.
  • Serves every state except Mississippi, with an in-person clinic in Tampa for local patients.

What to check first

  • No consult, lab or medication price is published. Ask a patient advocate for the full cost before you buy labs.
  • Its pages don't say whether your semaglutide or tirzepatide is brand or pharmacy-made. Ask which before you order.
  • Late-canceled or missed consults can be charged in full. Reschedule at least 24 hours ahead if plans change.
  • No pharmacy is named; orders go through a network of pharmacies. Ask which one will fill your prescription.
  • Its peptide page lists BPC-157, TB-500 and MOTS-c, which have no lawful compounding route. Skip those.

It fits you if

You want a GLP-1 prescribed after real testing and a long conversation, you'd like the choice of a shot, a dissolving tablet or drops, and you prefer paying per visit to a monthly plan.

Look elsewhere if

You want to see a monthly price before you hand over anything, a plan that bundles the visit and the drug, or a program that names its pharmacy and says plainly what kind of drug you get.

How Defy Medical scored

on the GLP-1 pill program lineup

25out of 100

  • Price0 of 35

    No comparable monthly total is established, so Price earns nothing.

  • Care15 of 25
    • Shown: Who prescribes
    • Shown: A clinician reviews your intake
    • Shown: Labs and who pays
    • Not shown: Follow-up schedule
    • Not shown: Dose changes at no new fee
  • Pharmacy0 of 25
    • Not shown: Pharmacy named
    • Not shown: Pharmacy state or type
    • Not shown: Brand or compounded is clear
    • Not shown: No "FDA-approved" claim for a compounded drug
  • Clarity10 of 15
    • Not shown: Price before the intake questions
    • Shown: Cancel and refund terms
    • Shown: States served

See the GLP-1 pill program lineupHow the score works

Three more providers to weigh

Questions about Defy Medical

How much does Defy Medical cost for semaglutide or tirzepatide?
Defy doesn't publish medication, consult or lab prices for its GLP-1s. You pay separately for labs, each consult and each medication order, and you see the drug price after your consult. There is no subscription.
Does Defy Medical offer GLP-1s without injections?
Yes. Its FAQ lists semaglutide and tirzepatide as a weekly injection, an oral disintegrating tablet or liquid drops. Liraglutide is a daily injection. Your provider recommends the form.
Is Defy Medical's semaglutide brand-name or compounded?
Its pages don't say. Ask your provider or patient advocate which product you'd receive before you order, because the brand drug and a pharmacy-made version are not the same thing.
Can I get a refund from Defy Medical?
Mostly no. Its terms say sales are final apart from account credits, consults aren't refunded once held, and dispensed medication can't be returned. Unused lab orders can be refunded within 90 days.
Which states does Defy Medical serve?
Every US state except Mississippi, which it says it can't serve under state telemedicine rules.

Read next

Picked for the same drugs and questions as this page.

  • Drug guideOral semaglutide: the three approved pills and how they differ

    Oral semaglutide is the active ingredient of Ozempic and Wegovy in a daily tablet. The FDA approved the Wegovy pill for weight reduction on December 22, 2025; Rybelsus and Ozempic tablets treat type 2 diabetes. In its 64-week trial, the 25 mg Wegovy pill cut weight 13.6% vs 2.2% on placebo. Self-pay through NovoCare runs $149–$299 a month.

  • Side by sideIs Foundayo as effective as Zepbound? What the trials show

    Both come from Eli Lilly, but they're different molecules in different forms. Zepbound produced about twice the average weight loss in its trial. Foundayo costs less, is a pill with no food rules, and may help hold on to weight lost on an injection.

  • Drug guideFoundayo (orforglipron): the daily GLP-1 pill, explained

    Foundayo is orforglipron, a once-daily GLP-1 pill from Eli Lilly that FDA approved on April 1, 2026 for weight management in adults. It's a different molecule from semaglutide and tirzepatide. The label says to take it with or without food. In its main trial, the top dose produced 11.2% average weight loss at 72 weeks.

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Where this review comes from

  • Defy Medical GLP-1 medication FAQ
  • Defy Medical Semaglutide, tirzepatide and weight-loss pages
  • Defy Medical peptide therapy page
  • Defy Medical terms of service and clinical procedures
  • Defy Medical vendor information and states FAQ

Every fact here comes from Defy Medical's own public pages. Partner fees aren't one of the four checks.