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LongevityGLP1

AgelessRx review

The short answer: AgelessRx prescribes low-dose rapamycin for $65 a month, with baseline and follow-up blood work included. Using rapamycin for aging is off-label.

By LongevityGLP1 desk, Publisher

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AgelessRx by the numbers

From
$65/mo · starting dose, month to month
Prescribes
Compounded tirzepatide microdose · Wegovy · Zepbound · Rapamycin
Prescriber
Online review or a video visit
Pharmacy
Not named on its site
States
All 50 states
Healthspan Score
78 out of 100

Our take on AgelessRx

AgelessRx is built around longevity prescriptions, and rapamycin is the clearest example. It's $65 a month, billed and shipped monthly, and that price includes baseline blood work and ongoing labs. That's unusual. Most programs bill labs separately, and rapamycin is a drug where monitoring matters. Keep in mind that rapamycin is approved for transplant medicine, not for aging, so any longevity prescription is off-label. AgelessRx offers compounded and generic rapamycin; ask which one you'll get, because the two aren't interchangeable milligram for milligram. The rapamycin guide covers what the human evidence does and doesn't show.

AgelessRx leans hard on PEARL, a year-long rapamycin trial its own team designed and ran. Read its claims with that in mind: the study's authors were AgelessRx employees or shareholders, and it missed its main goal, a change in visceral fat. Some secondary results, such as lean mass in women on the higher dose, looked better. That's a reason for caution, not a reason to skip the drug if your doctor thinks it fits.

For GLP-1s, the picture is mixed. The brand Wegovy pill runs about $349 a month once intro pricing ends: an AgelessRx membership plus the drug, which Amazon Pharmacy fills and bills separately. The first month is $199 all in. Microdose tirzepatide starts with a $109 first month, then bills every two months, about $159 a month. Its standard compounded GLP-1 plans only show a price on a four-month plan. The GLP-1 pill lineup compares the Wegovy pill route with other programs.

Care runs through a named medical group, Positron Medical Group, and you're charged only after a provider approves the prescription. Some states require a short video visit, and anyone can ask for one at no extra cost. Messaging and dose adjustments come with the plan. Compounded drugs come from licensed 503A or 503B pharmacies that AgelessRx doesn't name. Metformin is on the menu too; the metformin for longevity guide explains why it's also off-label for aging.

What AgelessRx costs

AgelessRx prices by product
ProductReal monthly cost
Compounded tirzepatide microdoseInjection$159/mo$318 every 2 months
RapamycinOral$65/moMonthly
WegovyTablet$349/moMonthly
WegovyInjection$414/moMonthly
ZepboundInjection$364/moMonthly

Prices are taken from AgelessRx's own site and current as of this update. Real monthly cost folds in required fees and turns four-week billing into calendar months; that's our math.

On its site, with the drug not named: GLP-1 injection: Starting at $139/mo.

Compounded tirzepatide microdose skips FDA approval: no one at the FDA judges whether it is safe, whether it works, or how well it was made before a pharmacy sends it out.

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Check AgelessRx's plans

What signing up looks like

  1. Complete the online intake

    Choose a treatment and answer the medical questions. Your card is charged only if a provider approves.

  2. A provider reviews it

    A U.S.-licensed provider from Positron Medical Group reviews your answers. Some states need a short video visit, at no extra cost.

  3. Labs and the pharmacy

    For rapamycin you complete blood work at a local lab; a licensed 503A or 503B pharmacy compounds the order.

  4. Free shipping, ongoing support

    Medication ships free each month, with provider messaging, check-ins and dose adjustments along the way.

Who prescribes, and the pharmacy

Prescriptions come from U.S.-licensed providers of Positron Medical Group, the medical group AgelessRx names in its privacy notice; review is online, with a short video visit where a state requires one or when you ask. AgelessRx says its compounding pharmacies are licensed 503A or 503B pharmacies. The Wegovy pill is filled by Amazon Pharmacy, which bills you directly.

Where AgelessRx does well

  • Rapamycin's monthly price includes baseline and ongoing blood work, not just the prescription.
  • Names its medical group, and your card is charged only after a provider approves you.
  • A video visit is available on request at no extra cost, even where the state doesn't require one.
  • Says every compounding pharmacy it uses is a licensed 503A or 503B pharmacy.
  • Prints the Wegovy pill's month-one, month-two and ongoing totals, membership included.

What to check first

  • Rapamycin for aging is off-label, and its own PEARL trial missed its main goal. Talk it through with your doctor first.
  • Rapamycin comes compounded or generic. Ask which you'll get, since doses don't convert one to one.
  • Microdose tirzepatide bills every two months after the intro month. Plan for the larger charge.
  • The Wegovy pill price is set by Amazon Pharmacy and can change. Check the drug price at each refill.
  • Standard compounded GLP-1 plans show a price only on a four-month plan. Ask for the month-to-month price.

It fits you if

You want a longevity-focused program for rapamycin or metformin with labs built in, or brand Wegovy pill access with a clear monthly total.

Look elsewhere if

You want compounded semaglutide or tirzepatide on a simple month-to-month plan, or a named compounding pharmacy.

How AgelessRx scored

on the longevity prescription lineup

78out of 100

  • Price28 of 35

    $65 a month at the starting dose, month to month, fees folded in. Full points at $40 or less, none at $160 or more.

  • Care20 of 25
    • Shown: Who prescribes
    • Shown: A clinician reviews your intake
    • Shown: Labs and who pays
    • Not shown: Follow-up schedule
    • Shown: Dose changes at no new fee
  • Pharmacy15 of 25
    • Not shown: Pharmacy named
    • Shown: Pharmacy state or type
    • Shown: Brand or compounded is clear
    • Shown: No "FDA-approved" claim for a compounded drug
  • Clarity15 of 15
    • Shown: Price before the intake questions
    • Shown: Cancel and refund terms
    • Shown: States served

Other lineups: Brand GLP-1 self-pay 86 · GLP-1 pill program 50

Also on these lineups: Wegovy pill programs: 7 of 10 · Rapamycin programs: 1 of 7

See the longevity prescription lineupHow the score works

Three more providers to weigh

Questions about AgelessRx

How much does rapamycin cost at AgelessRx?
$65 a month, billed and shipped monthly, with baseline and ongoing blood work included in that price.
Is rapamycin approved for longevity?
No. Rapamycin is FDA-approved for other uses, such as preventing transplant rejection. Prescribing it for healthy aging is off-label, so the decision rests with you and your provider.
What does the Wegovy pill cost through AgelessRx?
$199 for the first month and about $349 a month after the intro pricing ends, counting the AgelessRx membership and the drug billed by Amazon Pharmacy.
Does AgelessRx require a video visit?
Only in states that require one. Anyone can request a video visit, and AgelessRx says there's no extra cost for it.

Picked for the same drugs and questions as this page.

Still weighing AgelessRx?

Where this review comes from

  • AgelessRx rapamycin page
  • AgelessRx wegovy pill access page
  • AgelessRx metformin page
  • AgelessRx FAQ
  • AgelessRx medical group privacy notice

Every fact here comes from AgelessRx's own public pages. Partner fees aren't one of the four checks.