Arc-1 review
The short answer: Arc-1 lists rapamycin at $114.99 a month on a subscription, with no consult fee. It's off-label for aging, and Arc-1 doesn't say whether it's generic or compounded.
By LongevityGLP1 desk, Publisher
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Arc-1 by the numbers
- From
- $115/mo · starting dose, month to month
- Prescribes
- Compounded semaglutide · Compounded tirzepatide · Rapamycin
- Prescriber
- A clinician reviews your answers online
- Pharmacy
- Not named on its site
- States
- 46 states
- Healthspan Score
- 33 out of 100
Our take on Arc-1
Arc-1 is a longevity storefront first, and rapamycin is the product that sets it apart. The subscription price is $114.99 a month, with free shipping and no consultation fee; a one-time order costs more. Rapamycin is approved for transplant medicine, not for aging, so a longevity prescription is off-label. Two details are missing from the product page. It never says whether the capsules are generic sirolimus or compounded, and it doesn't print the capsule strength, so you can't tell how long a 12-capsule pack lasts. Ask both before you order. The rapamycin guide covers what the human evidence does and doesn't show.
The order of steps is unusual. You pay at checkout first, then fill in the intake forms, and a practitioner reviews them afterward. If something needs clarifying, a practitioner reaches out by chat, phone or video. Arc-1 doesn't say what happens to your payment if you aren't approved, and its two policies on returns disagree: the refund policy offers a 30-day return window on unused items, while the support page says prescriptions generally can't be returned. Get the answer in writing from support before you pay.
For GLP-1s, compounded semaglutide starts at $199.99 a month at the lowest dose, and compounded tirzepatide at $199.99. Both prices rise with the dose, and the higher-dose prices show only once you add a dose to the cart. The tirzepatide page still advertises a lower starting figure than the cart charges; the cart price is the one you pay. Tirzepatide is compounded with glycine and B12. One more thing to know: the semaglutide page calls the drug FDA-approved, which is true of Wegovy and Ozempic but not of a compounded version.
Arc-1's founder, Dr. Todd Stearns, is named on the site, and you can book a 20-minute consult with him from the homepage, though no price is shown for it. The prescribing practitioners themselves aren't named, and neither are the pharmacies; the pages say only that US-licensed compounding pharmacies fill orders. Most products don't ship to Arkansas, Indiana, Minnesota, Puerto Rico or South Carolina. Arc-1 also sells metformin, NAD+, sermorelin and glutathione. The metformin and rapamycin lineup scores it against other longevity programs.
What Arc-1 costs
| Product | Real monthly cost | |
|---|---|---|
| Compounded semaglutideInjection | $199.99/mo | $199.99/mo |
| Compounded tirzepatideInjection | $199.99/mo | $199.99/mo |
| RapamycinCapsule | $114.99/mo | $114.99/mo |
Prices are taken from Arc-1's own site and current as of this update. Real monthly cost folds in required fees and turns four-week billing into calendar months; that's our math.
Compounded semaglutide skips FDA approval: no one at the FDA judges whether it is safe, whether it works, or how well it was made before a pharmacy sends it out.
Want Arc-1's current price for your dose?
Your monthly price is the same through our link.
What signing up looks like
Choose a product and check out
Pick a treatment and dose, then complete checkout. There's no consultation fee, and a subscription lowers the refill price.
Fill in the intake forms
After checkout you complete electronic intake forms about your health history and goals.
A practitioner reviews them
A licensed practitioner reviews your forms and may follow up by chat, phone or video before approving.
Ships free, refills online
A US-licensed pharmacy fills the order and it ships free. Refills and delivery timing are managed from your account.
Who prescribes, and the pharmacy
Licensed practitioners in what Arc-1 calls a board-certified physician network review your intake, mostly in writing, with chat, phone or video when they need more information; only the founder, Dr. Todd Stearns, is named. Arc-1 says US-licensed compounding pharmacies working in FDA-registered facilities dispense its compounded drugs, but its terms, privacy, refund and support pages don't name a pharmacy or say where it's licensed.
Where Arc-1 does well
- Rapamycin is sold on a monthly subscription with its price on the product page, with no consult fee.
- Names its founder, a board-certified physician, and lets you book a 20-minute consult with him.
- Free shipping, and a Chat with Doctor button in your account goes straight to your prescriber.
- Prints the states each product can't ship to on the product page itself.
- Sells rapamycin, metformin and GLP-1s from one account, with refills managed in one place.
What to check first
- Rapamycin's page doesn't say generic or compounded, or the capsule strength. Ask both before you order.
- You pay before the intake is reviewed. Ask support what's refunded if you aren't approved.
- The semaglutide page calls the drug FDA-approved; compounded versions aren't. Read it as Wegovy's status only.
- GLP-1 prices rise with the dose and show only in the cart. Check the price at your likely dose first.
- Its refund and support pages disagree on returns, and no cancel terms are printed. Get the rules in writing.
It fits you if
You want rapamycin or metformin on a simple monthly subscription with no consult fee, and you're comfortable asking a few questions before you pay.
Look elsewhere if
You want a clinician to approve you before you're charged, a named pharmacy, or written cancellation terms.
How Arc-1 scored
on the longevity prescription lineup
33out of 100
- Price13 of 35
$115 a month at the starting dose, month to month, fees folded in. Full points at $40 or less, none at $160 or more.
- Care5 of 25
- Not shown: Who prescribes
- Shown: A clinician reviews your intake
- Not shown: Labs and who pays
- Not shown: Follow-up schedule
- Not shown: Dose changes at no new fee
- Pharmacy5 of 25
- Not shown: Pharmacy named
- Not shown: Pharmacy state or type
- Shown: Brand or compounded is clear
- Not shown: No "FDA-approved" claim for a compounded drug
- Clarity10 of 15
- Shown: Price before the intake questions
- Not shown: Cancel and refund terms
- Shown: States served
Other lineups: Compounded semaglutide 37 · Compounded tirzepatide 47
Also on these lineups: Semaglutide programs that also treat low testosterone: 32 of 36 · Tirzepatide programs that also treat low testosterone: 25 of 34 · Compounded tirzepatide under $250 a month: 36 of 36 · Compounded semaglutide under $200 a month: 41 of 41 · Rapamycin programs: 7 of 7
Three more providers to weigh
AgelessRx
From $65/mo
bmiMD
PartnerFrom $55/mo
HealthRX
PartnerFrom $134/mo
Questions about Arc-1
- How much does rapamycin cost at Arc-1?
- The subscription price is $114.99 a month with free shipping and no consultation fee. A one-time order without a subscription costs more.
- Is Arc-1's rapamycin generic or compounded?
- The product page doesn't say, and it doesn't print the capsule strength either. Ask support before you order, because the answer changes what you're getting.
- Do I pay before a clinician reviews my request at Arc-1?
- Yes. Checkout comes first and the intake forms follow. Ask support what's refunded if the practitioner doesn't approve the prescription.
- How much is compounded semaglutide at Arc-1?
- It starts at $199.99 a month at the lowest dose and rises at higher doses, which appear in the cart. Compounded tirzepatide also starts at $199.99.
- Which states can't order from Arc-1?
- Most products don't ship to Arkansas, Indiana, Minnesota, Puerto Rico or South Carolina, and some, such as tirzepatide and NAD+, also exclude California.
Read next
Picked for the same drugs and questions as this page.
- ResearchMetformin and tiredness: what's common, what's a warning sign
How often metformin causes weakness or headache, why long-term use can lower vitamin B12, and the rare kind of sleepiness that needs care right away.
- Drug guideMetformin: what it does, what it's approved for, and what's hype
Metformin lowers blood sugar in type 2 diabetes, mainly by reducing the glucose your liver releases and helping your body use insulin. It is FDA-approved only for type 2 diabetes. People also take it off-label for prediabetes, weight or aging, but the trial evidence for those uses is weaker or, for aging, missing.
- Side by sideIs metformin like Ozempic? Two very different diabetes drugs
One is a decades-old generic tablet, the other a weekly injection with heart and kidney labels. They treat the same disease in different ways, and many people take both.
- ResearchHow people get a rapamycin prescription for longevity
Rapamycin is a transplant drug that some clinicians prescribe off-label for aging. Here is how the prescription works, what programs charge, and what to avoid.
Still weighing Arc-1?
Where this review comes from
- Arc-1 rapamycin product page
- Arc-1 compounded semaglutide product page
- Arc-1 compounded tirzepatide product page
- Arc-1 how we work page
- Arc-1 refund policy and support page
Every fact here comes from Arc-1's own public pages. Partner fees aren't one of the four checks.