Compounded oral semaglutide programs, scored
Monthly cost at the starting dose, fees folded in.
26 of the 40 programs on our scored GLP-1 pills lineup are compounded oral semaglutide programs. Their starting-dose plates run $127 to $369 a month, and the highest Healthspan Score among them is 75, held by Nova.
Who is on this list: On the GLP-1 pill lineup, the program prescribes a compounded semaglutide you swallow or dissolve under the tongue.
Back to the full GLP-1 pills lineup
Partner programs on this lineup
Partners: start care through one of these and the provider may pay us, at no extra cost to you. The full lineup below stays in Healthspan Score order.
ShedPartner
Healthspan Score 75from $199/mo
Partners on this lineup are labeled. We may be paid when you start care through their links.
Sorted by Healthspan Score, highest first.
- 1Price35Care10Pharmacy15Clarity15See Nova pricing75Healthspan Scorefrom$127/mo
- 2
ShedPartner
Semaglutide lozenges and drops priced by dose, with free follow-up visits.
Price25Care10Pharmacy25Clarity15See Shed pricing75Healthspan Scorefrom$199/mo - 3Price34Care15Pharmacy15Clarity10See PlexusDx pricing74Healthspan Scorefrom$149/mo
- 4
Semaglutide and tirzepatide lozenges at a flat monthly price, no membership.
No membershipPrice34Care10Pharmacy20Clarity10See Youth & Soul pricing74Healthspan Scorefrom$149/mo - 5Price27Care15Pharmacy15Clarity15See June Health pricing72Healthspan Scorefrom$187/mo
- 6
LttlPartner
A dissolving semaglutide tablet, priced monthly with a cheaper first month.
Price20Care10Pharmacy20Clarity15See Lttl pricing65Healthspan Scorefrom$229/mo - 7
MEDGmPartner
Daily dissolvable semaglutide tablets with labs and clinician access included.
Dissolvable tabletPrice0Care25Pharmacy25Clarity15See MEDGm pricing65Healthspan Scorefrom$369/mo - 8
Semaglutide and tirzepatide drops under the tongue; final price set by your dose.
Needle-free dropsPrice17Care10Pharmacy25Clarity10See Try Ageless pricing62Healthspan Scorefrom$249/mo - 9
Luvo HealthPartner
Compounded semaglutide tablet on the same four-week cycle.
Price12Care10Pharmacy25Clarity15See Luvo Health pricing62Healthspan Scorefrom$281/mo - 10Price12Care20Pharmacy20Clarity10See You + Me MD pricing62Healthspan Scorefrom$279/mo
- 11Price25Care10Pharmacy10Clarity15See Nirwana Health pricing60Healthspan Scorefrom$199/mo
- 12Price25Care10Pharmacy10Clarity15See WePeptideRx pricing60Healthspan Scorefrom$199/mo
- 13
Compounded semaglutide or tirzepatide as a daily dissolving tablet.
Price25Care10Pharmacy15Clarity10See YourHealthRx pricing60Healthspan Scorefrom$200/mo - 14Price8Care15Pharmacy20Clarity15See Prime Doctor RX pricing58Healthspan Scorefrom$302/mo
- 15
RxSpan MDPartner
Every plan length priced up front, with capsule options for both molecules.
Capsules tooPrice17Care10Pharmacy20Clarity10See RxSpan MD pricing57Healthspan Scorefrom$249/mo - 16Price0Care15Pharmacy25Clarity15See MEDVi pricing55Healthspan Scorefrom$369/mo
- 17Price9Care15Pharmacy20Clarity10See ElleS pricing54Healthspan Scorefrom$299/mo
- 18
Compounded semaglutide dissolving tablet, one product-page price, named Texas pharmacy.
Needle-free tabletPrice9Care5Pharmacy25Clarity15See MangoRx pricing54Healthspan Scorefrom$299/mo - 19
One-, three- and six-month supplies, a named pharmacy and a tablet option.
Names its pharmacyPrice9Care10Pharmacy20Clarity15See Nu Image Medical pricing54Healthspan Scorefrom$299/mo - 20
DirectMedsPartner
Needle-free semaglutide drops under the tongue, priced below the shot.
Price17Care10Pharmacy15Clarity10See DirectMeds pricing52Healthspan Scorefrom$249/mo - 21
Daily dissolving tirzepatide or semaglutide tablets, month to month.
Price12Care20Pharmacy10Clarity10See Neuvé MD pricing52Healthspan Scorefrom$279/mo - 22
SkinnyRxPartner
Daily compounded tirzepatide or semaglutide tablets with overnight shipping.
Daily tabletsPrice9Care10Pharmacy15Clarity15See SkinnyRx pricing49Healthspan Scorefrom$299/mo - 23
Daily sublingual semaglutide after a physician video visit; membership extra.
Video visitPrice4Care15Pharmacy15Clarity15See ElitePhysiqMD pricing49Healthspan Scorefrom$328/mo - 24Price9Care10Pharmacy10Clarity10See Willow pricing39Healthspan Scorefrom$299/mo
- 25Price0Care5Pharmacy15Clarity10See Iron Med Rx pricing30Healthspan ScoreNo monthly price to compare
- 26
Monthly check-ins advertised, with prescription cost and pharmacy identity unresolved
Price0Care10Pharmacy10Clarity5See Ryze Rx pricing25Healthspan ScoreNo monthly price to compare
The whole lineup at a glance
| Provider | Score | Form | Per month | Price · Care · Pharmacy · Clarity |
|---|---|---|---|---|
| Nova, position 1 | 75 | Sublingual, compounded | $127/mo | 35 · 10 · 15 · 15 |
| ShedPartner, position 2 | 75 | Lozenge (troche), compounded | $199/mo | 25 · 10 · 25 · 15 |
| PlexusDx, position 3 | 74 | Dissolving tablet, compounded | $149/mo | 34 · 15 · 15 · 10 |
| Youth & Soul, position 4 | 74 | Sublingual, compounded | $149/mo | 34 · 10 · 20 · 10 |
| June Health, position 5 | 72 | Tablet, compounded | $187/mo | 27 · 15 · 15 · 15 |
| LttlPartner, position 6 | 65 | Dissolving tablet, compounded | $229/mo | 20 · 10 · 20 · 15 |
| MEDGmPartner, position 7 | 65 | Dissolving tablet, compounded | $369/mo | 0 · 25 · 25 · 15 |
| Try Ageless, position 8 | 62 | Sublingual, compounded | $249/mo | 17 · 10 · 25 · 10 |
| Luvo HealthPartner, position 9 | 62 | Tablet, compounded | $281/mo | 12 · 10 · 25 · 15 |
| You + Me MD, position 10 | 62 | Tablet, compounded | $279/mo | 12 · 20 · 20 · 10 |
| Nirwana Health, position 11 | 60 | Tablet, compounded | $199/mo | 25 · 10 · 10 · 15 |
| WePeptideRx, position 12 | 60 | Tablet, compounded | $199/mo | 25 · 10 · 10 · 15 |
| YourHealthRx, position 13 | 60 | Dissolving tablet, compounded | $200/mo | 25 · 10 · 15 · 10 |
| Prime Doctor RX, position 14 | 58 | Tablet, compounded | $302/mo | 8 · 15 · 20 · 15 |
| RxSpan MDPartner, position 15 | 57 | Capsule, compounded | $249/mo | 17 · 10 · 20 · 10 |
| MEDVi, position 16 | 55 | Dissolving tablet, compounded | $369/mo | 0 · 15 · 25 · 15 |
| ElleS, position 17 | 54 | Capsule, compounded | $299/mo | 9 · 15 · 20 · 10 |
| MangoRx, position 18 | 54 | Dissolving tablet, compounded | $299/mo | 9 · 5 · 25 · 15 |
| Nu Image Medical, position 19 | 54 | Sublingual, compounded | $299/mo | 9 · 10 · 20 · 15 |
| DirectMedsPartner, position 20 | 52 | Sublingual, compounded | $249/mo | 17 · 10 · 15 · 10 |
| Neuvé MD, position 21 | 52 | Tablet, compounded | $279/mo | 12 · 20 · 10 · 10 |
| SkinnyRxPartner, position 22 | 49 | Tablet, compounded | $299/mo | 9 · 10 · 15 · 15 |
| ElitePhysiqMD, position 23 | 49 | Sublingual, compounded | $328/mo | 4 · 15 · 15 · 15 |
| Willow, position 24 | 39 | Tablet, compounded | $299/mo | 9 · 10 · 10 · 10 |
| Iron Med Rx, position 25 | 30 | — | No monthly price to compare | 0 · 5 · 15 · 10 |
| Ryze Rx, position 26 | 25 | — | No monthly price to compare | 0 · 10 · 10 · 5 |
How this lineup is built
Each program here prescribes compounded semaglutide in a form you take by mouth: a drop or spray under the tongue, a lozenge, a tablet that dissolves on the tongue, or a capsule or tablet you swallow. A compounding pharmacy makes it for your prescription. None of these products is FDA-approved, and none has been tested in a clinical trial of its own.
Scores come from the full GLP-1 pill lineup, where each program is placed on one starting-dose pill price. Usually that's the compounded semaglutide product, but a program that also sells another pill can be placed on that one instead; the line under each name says which.
Many oral forms, one unanswered question about each
Programs on this list sell the same molecule in several shapes. The shape changes how you take it every day, and it may change how much semaglutide reaches your blood. For the compounded forms, nobody has published that number.
That's the core difference from the brand pill. The Wegovy tablet pairs semaglutide with an absorption enhancer called SNAC, and its label still estimates that only about 1% to 2% of a dose is absorbed. A compounded drop or lozenge may or may not contain an enhancer, and the pharmacy's recipe isn't public.
So compare programs first on what they'll tell you about the product. Does the program name the pharmacy, say what's in the formula besides semaglutide, and give the form plainly? The Pharmacy chip rewards exactly that.
Then compare the plan: price at the starting strength, whether the price rises as the strength does, and whether you can switch to an injection on the same plan if the oral form doesn't suit you.
How the oral forms differ
- Sublingual drops or sprays. Held under the tongue for a set time. Ask how each dose is measured and what the label tells you to do.
- Lozenges and troches. Dissolved slowly in the mouth. Flavoring and size vary by pharmacy.
- Orally disintegrating tablets. Dissolve on the tongue within moments, without water.
- Capsules and swallowed tablets. The closest in shape to the brand pill, but not the same formulation, and they aren't the Wegovy tablet even when they look alike.
- One thing in common. Each is a pharmacy preparation for an individual prescription, with the strength and instructions set by your prescriber and the pharmacy label.
Compounded oral prices next to the brand pill
Plates here run $127 to $369 a month at the starting strength, required fees included. The middle plate, $264, comes to about $3,168 over a year by our math.
Across every program we track, 23 list compounded semaglutide in a form you take by mouth at $127–$369 a month, with a median of $249.
Now the comparison that surprises people. Through telehealth programs, the FDA-approved Wegovy pill runs $149–$350 a month, with a median of $298. At the starting dose, many compounded oral plans here cost about as much, and NovoCare's own self-pay price for the brand pill's first dose is lower than most of them.
That doesn't settle it for everyone. Some compounded plans keep one price at every strength, and some people want a drop or lozenge rather than a tablet with a fasting rule. But it's worth pricing the Wegovy pill programs before you choose.
How to read this lineup
- Every program here prescribes a compounded semaglutide you take by mouth. Scores and their parts come unchanged from the full GLP-1 pill lineup.
- The plate is the starting-dose price of the pill each program is placed on in that lineup, with required fees added. Check the line under the name for the form.
- Partner-tagged programs may pay us if you start care through our link. The tag changes the button, not the order, and the labeled Partner box above the list is separate from it.
- “No monthly price to compare” (2 here) marks a program whose pages don't give one month-to-month starting price, so its price part scores zero.
Ask these before you choose a compounded oral form
- Which form is this exactly, and how do I take it each day?
- Which pharmacy makes it, and does the label list every ingredient?
- Does the formula include an absorption enhancer, and is there any data on how much is absorbed?
- Does the price change as my strength goes up?
- Can I move to an injection, or to the brand pill, on the same plan?
- Who do I contact about side effects, and how fast do they answer?
Questions about this lineup
- Does compounded oral semaglutide work?
- No trial has tested a compounded drop, lozenge or tablet, so there's no published result to point to. The brand Wegovy pill was tested in its own trials, and even it absorbs only about 1% to 2% of each dose, according to its label.
- How much is compounded oral semaglutide a month?
- On this page, starting plates run $127 to $369 a month with required fees included. Across all programs we track, it lists at $127–$369.
- Is a compounded semaglutide tablet the same as the Wegovy pill?
- No. The Wegovy pill is an FDA-approved tablet made by Novo Nordisk with an absorption enhancer called SNAC. A compounded tablet is a pharmacy's own formulation, isn't FDA-approved and has no trial data.
- Is sublingual semaglutide better than a swallowed tablet?
- There's no answer yet. No trial has compared compounded oral forms with each other or with the brand pill. Choose the form you can take every day, and ask the program what it knows about absorption.
The Healthspan Score
Every provider gets a 0 to 100 Healthspan Score for each drug it prescribes, built from four checks: what a new patient pays per month at the starting dose (35), how care works (25), whether the pharmacy is named (25) and how clearly prices and terms are shown (15).
How the Healthspan Score works · By Grant Ebbesen, Pricing and provider data · Updated October 2026